BADERC has established a relationship with the Broad Institute of Harvard and MIT, aiming to facilitate and support BADERC investigators whose projects would benefit from collaboration with the unusual platform capabilities at the Broad Institute.    The relationship includes facilitating interactions between BADERC investigators and Platform leadership, and modest amounts of funding for approved projects.

Background
Broad has a number of scientific “Platforms”: professionally managed organizations whose mission is to develop and manage capabilities outside the scope of individual laboratories.   Platforms have expertise in high throughput laboratory technologies, application development, process optimization, project management, bioinformatics and software engineering.   Broad platforms are financially self-supporting (other than when starting up), and thus recover costs through user fees.

The Platforms include Genome Sequencing, Genetic Analysis, Biological Samples, Proteomics, Metabolite Profiling, Imaging, Chemical Biology, and RNAi.   Additional information about each Platform is available at following URL:

http://www.broadinstitute.org/scientific-community/science/platforms/platforms

Due to limited bandwidth, capacity and funding, in many cases Broad platforms are forced to prioritize among potential projects.  To facilitate collaboration with the diabetes research community, BADERC has met with leaders of particular platforms and set aside a modest amount of funding to support the work required by the Platform.  While in principle any Platform can be considered, among those that may be particularly relevant to the diabetes community include metabolite profiling, genetic analysis and genome sequencing, imaging and chemical biology. 

Investigators interested in such collaborations can begin by contacting either Jose Florez (jcflorez@partners.org) and / or David Altshuler (altshuler@molbio.mgh.harvard.edu), who will help make connections with the relevant Platform.   Investigators requesting funding support will be asked to write a brief (2 page) proposal that will be reviewed for feasibility with the relevant Platform, and for funding priority by a BADERC committee. 

The total funding available to support platform activities is $100,000, to be spread across multiple projects (recognizing that some projects may have larger scope than others).  Funding may be updated with each renewal cycle.

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